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9 mar 2017 · Kaplan-Meier survival curve estimates and corresponding log-rank tests were computed based on the data sets of AML96, AML96 patients ≤60 years, AML96 patients >60 years, AML96 patients with adverse-risk cytogenetics, AML2003, and AML2003 patients with adverse-risk cytogenetics, respectively.
4 nov 2019 · Although all cases of AML-NPM1, by definition, demonstrate an NPM1 mutation, NPM1 mutations typically do not occur in isolation. 1,4 Most commonly, comutations occur in the FLT3 gene (including both FLT3–internal tandem duplication [ITD] and FLT3–tyrosine kinase domain [TKD] mutations) and in genes regulating DNA methylation, such as DNMT3A, TET2, IDH1, and IDH2. 7 DNA methylation ...
22 feb 2024 · What the EU is doing and why. The Anti-Money Laundering and Countering the Financing of Terrorism Authority (AMLA) will be a decentralised EU agency that will coordinate national authorities to ensure the correct and consistent application of EU rules. The aim of the EU Authority will be to transform the anti-money laundering and countering the ...
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To improve outcomes in the treatment of AML, the Japan Adult Leukemia Study Group has conducted six studies in AML patients aged 15-64 years since 1987. In AML201 study, IDR (12 mg/m (2)/day for 3 days) or DNR (50 mg/m (2)/day for 5 days) in combination with Ara-C (100 mg/m (2)/day continuous infusion for 7 days) was established as the standard ...
12 ago 2010 · We present an analysis of prognostic factors derived from a trial in patients with acute myeloid leukemia older than 60 years. The AML96 trial included 909 patients with a median age of 67 years (range, 61-87 years). Treatment included cytarabine-based induction therapy followed by 1 consolidation.
21 mar 2023 · Acute myeloid leukemia (AML) is a rare cancer that affects your bone marrow and blood. It’s an aggressive cancer that, left untreated, may be life-threatening.
