Annunci
relativi a: cell based therapy designTools & support for applications within the different stem cell workflows. Reprogramming, culture, engineering, differentiation, characterization.
24/7 Monitoring and Support for Critical Advanced Therapy Shipments. Expert Supply Chain Coordination by a Dedicated Catalent Case Manager
Risultati di ricerca
30 mag 2022 · The widespread clinical translation and commercialization of cell-based therapies are hampered by challenges related to cell source, viability, potency, safety and scalability.
30 mag 2022 · A combined approach to genetically engineer the human genome, epigenetically engineer the human transcriptome, and to tailor culturing conditions and small-molecule cocktails will likely resolve these inefficiencies and help to usher in the next wave of cell-based therapeutics.
- 10.1038/s41573-022-00476-6
- 2022
- Nat Rev Drug Discov. 2022; 21(9): 655-675.
15 lug 2024 · Drug delivery systems at the nanoscale, microscale and macroscale can be designed to improve cell therapies by optimizing pharmacokinetics, cell function and cell viability, and by preventing...
In this review, we introduce a range of applications for engineering primary cells and stem cells for cell-based therapies. We highlight tools and advances that have launched mammalian cell engineering from bioproduction to precision editing of therapeutically relevant cells.
2 giorni fa · Adoptive cell therapies engineered to express chimeric antigen receptors (CARs) or transgenic T cell receptors (TCRs) to recognize and eliminate cancer cells have emerged as a promising approach ...
Cell-based therapeutics are an emerging modality with the potential to treat many currently intractable diseases through uniquely powerful modes of action.
In this review, we introduce a range of applications for engineering primary cells and stem cells for cell-based therapies. We highlight tools and advances that have launched mammalian cell engineering from bioproduction to precision editing of therapeutically relevant cells.
Annunci
relativi a: cell based therapy designTools & support for applications within the different stem cell workflows. Reprogramming, culture, engineering, differentiation, characterization.
24/7 Monitoring and Support for Critical Advanced Therapy Shipments. Professional end-to-end supply chain management for advanced therapies
