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5 gen 2017 · The potency ratio of prednisone to deflazacort is about 1:1.3; e.g., 8 mg of deflazacort elicits a similar biological response to 6 mg of prednisone. The dose equivalence of orally administered deflazacort and prednisone has been evaluated in a large US trial.
- Luca Parente
- 10.1186/s40360-016-0111-8
- 2017
- BMC Pharmacol Toxicol. 2017; 18: 1.
Converts steroid dosages using dosing equivalencies. INSTRUCTIONS. These dose relationships only apply to oral or IV administration. Glucocorticoid potencies may differ greatly following intramuscular or intra-articular administration. When to Use. Pearls/Pitfalls. Why Use. Converting From: Betamethasone (IV) Cortisone (PO) Dexamethasone (IV or PO)
Clinical studies have indicated that the average potency ratio of deflazacort to prednisolone is 0.69–0.89 and 6 mg of deflazacort is equivalent to 5 mg of prednisolone. However, the therapeutic dosage ratio has been reported to range from 1:1.2 to 1:1.5. 1
- Surajit Nayak, Basanti Acharjya
- 2008
5 gen 2017 · Short conclusion: We suggest that this new conversion table could be a useful tool for physicians who need to select the appropriate dose of deflazacort in their clinical practice. Keywords: Corticosteroids; Deflazacort; Equipotency ratio; Relative potencies; Therapeutic efficacy; Tolerability.
- Luca Parente
- 2017
Article Details. Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids. BMC Pharmacol Toxicol. 2017 Jan 5;18 (1):1. doi: 10.1186/s40360-016-0111-8. BACKGROUND: Deflazacort is a synthetic corticosteroid characterized by a favourable pharmacokinetic profile, peculiar pharmacodynamic properties and a ...
5 gen 2017 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" "breast cancer"
5 gen 2017 · Deflazacort (DFZ) es un glucocorticoide ozaxolínico sintético derivado de la prednisolona (1)(2)(3)(4), el cuál fue patentado en el año 1966 (4).
