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12 ore fa · The high malignant degree and poor prognosis of pancreatic cancer (PC) pose severe challenges to the basic research and clinical translation of next-generation therapies. The rise of immunotherapy has improved the treatment of a variety of solid tumors, while the application in PC is highly restricted by the challenge of immunosuppressive tumor microenvironment.
12 ore fa · These carcinogens induce different aspects of malignant transformation of FTE cells including DNA double-strand breaks, stemness activation, clonal expansion, anoikis resistance, AIG, migration, invasion, and xenograft tumorigenesis [14,15,16, 21]. PF appears to acquire these oncogenic factors and the associated activities from FF.
12 ore fa · KEY TAKEAWAYS The study aimed to investigate the correlation between disulfidptosis and lncRNAs in patients with SKCM for targeted treatment insights. The findings unveiled a risk model of disulfidptosis-related lncRNAs for predicting SKCM patient prognosis and guiding personalized treatments. Skin cutaneous melanoma (SKCM) is a highly aggressive form of malignant melanoma, characterized by ...
12 ore fa · The RNA world is wide, and besides mRNA, there is a variety of other RNA types, such as non-coding (nc)RNAs, which harbor various intracellular regulatory functions. This review focuses on small interfering (si)RNA and micro (mi)RNA, which form a complex network regulating mRNA translation and, consequently, gene expression. In fact, these RNAs are critically involved in the function and ...
12 ore fa · Strabismus surgery is a procedure to correct misaligned eyes and improve vision. Malignant hyperthermia is a rare but life-threatening condition triggered by certain anesthesia drugs. There is a potential connection between strabismus surgery and malignant hyperthermia, although the exact link is not fully understood.
2 ore fa · Skin cancer survivor and cancer motivational speaker Naniki Seboni speaks with Mediclinic after her stage 3 malignant melanoma cancer diagnosis and the misco...
12 ore fa · Then, due to the suspicion of malignant brain tumor, both intracranial lesions were surgically resected. However, the pathological results only displayed chronic suppurative inflammation, with lymphocytic infiltration and vasculitis (K). Treponema pallidum was detected by the metagenome next-generation sequencing.
