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  1. A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. Typically it is used for cases when a risk to health will potentially result. An overdose may result in a toxic state or death.

  2. L'overdose è un'urgenza medica che può presentarsi in persone che assumono sostanze stupefacenti . Un esempio frequente di overdose è quella ottenuta con l'assunzione di dosi eccessive di eroina; essendo l'eroina un sedativo del sistema nervoso centrale, essa agisce sui centri respiratori e può comportare il coma, con decesso per asfissia.

  3. The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs called opiates/ opioids since the 1990s. It includes the significant medical, social, psychological, demographic and economic consequences of ...

  4. Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder. Differing definitions of drug abuse are used in public health, medical, and criminal justice contexts.