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  1. over 110,000 (2017) An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3] [5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3]

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  3. None approved, experimental only. Cannabis use disorder ( CUD ), also known as cannabis addiction or marijuana addiction, is a psychiatric disorder defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders ( DSM-5) and ICD-10 as the continued use of cannabis despite clinically significant impairment.

  4. A combination drug or a fixed-dose combination (FDC) is a medicine that includes two or more active ingredients combined in a single dosage form. Terms like "combination drug" or "combination drug product" can be common shorthand for an FDC product (since most combination drug products are currently FDCs), although the latter is more precise if in fact referring to a mass-produced product ...

  5. Barbiturate overdose. Barbiturate overdose is poisoning due to excessive doses of barbiturates. [8] Symptoms typically include difficulty thinking, poor coordination, decreased level of consciousness, and a decreased effort to breathe ( respiratory depression ). [1] Complications of overdose can include noncardiogenic pulmonary edema. [2]

  6. en.wikipedia.org › wiki › Heath_LedgerHeath Ledger - Wikipedia

    Heath Ledger. Heath Andrew Ledger (4 April 1979 – 22 January 2008) was an Australian actor. After playing roles in several Australian television and film productions during the 1990s, he moved to the United States in 1998 to further develop his film career. His work consisted of 20 films in a variety of genres, including 10 Things I Hate ...

  7. Wernicke-Korsakoff syndrome ( WKS) is the combined presence of Wernicke encephalopathy (WE) and alcoholic Korsakoff syndrome (AKS [clarification needed] ). Due to the close relationship between these two disorders, people with either are usually diagnosed with WKS as a single syndrome. It mainly causes vision changes, ataxia and impaired memory.