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  1. Combined drug intoxication (CDI), or multiple drug intake (MDI), is a cause of death by drug overdose from poly drug use, often implicated in polysubstance dependence. Deaths by combined drug intoxication are relatively rare (one in several million).

  2. Combined drug intoxication. Combined drug intoxication use often carries with it more risk than use of a single drug, due to an increase in side effects, and drug synergy.

  3. Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals.

  4. Combined drug intoxication (CDI) happens when a person ingests multiple drugs at one time. Drug users may consume multiple substances on accident—for example, in the case of laced drugs—or intentionally, to heighten their effects.

  5. 6 feb 2024 · Combined drug intoxication (CDI), also known as multiple drug intake (MDI) or polydrug use, is the effect of abusing multiple drugs. It occurs when an individual combines more than one drug or multiple substances at a time. Polydrug use is not limited to illicit substances.

  6. 1 gen 2013 · We use this approach to show that commonly used drug regimens function by minimizing the effect of genetic diversity on therapeutic response, whereas, in contrast, less used synergistic drug combinations amplify the impact of patient genotype on component drug efficacy.

  7. 21 ago 2023 · The latest federal priorities for addressing the overdose and addiction epidemic, including a focus on drugs used in combination and treatment efforts. On-the-ground harm reduction efforts, including increasing access to naloxone, test strips, and syringe service programs.