Risultati di ricerca
11 ott 2023 · Definition / general. Prototype of autoimmune disease presenting with goiter, elevated circulating antithyroid antibodies, often with hypothyroidism. Histopathologically diffuse lymphoplasmacytic infiltration, lymphoid follicle formation, follicular atrophy, oncocytic metaplasia and fibrosis.
- Hashimoto-fibrous
Riedel’s thyroiditis: adherence to adjacent structures with...
- Hashimoto-fibrous
29 lug 2023 · The pathophysiology of Hashimoto thyroiditis involves the formation of antithyroid antibodies that attack the thyroid tissue, causing progressive fibrosis. The diagnosis can be challenging, and consequently, the condition is sometimes not diagnosed until late in the disease process.
- Dana L. Mincer, Ishwarlal Jialal
- 2023/07/29
- VA MEDICAL CENTER, MATHER , CA
17 dic 2020 · Clearly much needs to be done to understand whether these changes have any aetiological significance but a role for microbiota would fit with old observations in experimental autoimmune thyroiditis, in which animals raised in specific-pathogen-free conditions had lower levels of thyroiditis and thyroglobulin antibodies .
- A P Weetman
- 2021
3 mar 2022 · Hashimoto thyroiditis (HT) is a common autoimmune disorder, affecting women 7–10 times more often than men, that develops because of genetic susceptibility, X chromosome inactivation patterns modulated by environmental factors as well as microbiome composition, and leads to an imbalance in self-tolerance mechanisms.
- Joanna Klubo-Gwiezdzinska, Leonard Wartofsky
- 2022/03/03
- 10.20452/pamw.16222
26 gen 2022 · Follicular destruction is the characteristic pathologic hallmark of thyroiditis. The cause of what is most commonly referred to as Hashimoto's thyroiditis is thought to be a combination of genetic susceptibility and environmental factors.
Hashimoto’s thyroiditis (HT), the most frequent autoimmune thyroid disorders (AITDs), is the leading cause of hypothyroidism in the iodine-sufficient areas of the world. About 20-30% of patients suffers from HT, whose cause is thought to be a combination of genetic susceptibility and environmental factors that causes the loss of
The pathologic features of lymphocytic infiltration, especially of T cells, and follicular destruction are the histological hallmark of autoimmune thyroiditis (AIT), that lead to gradual atrophy and fibrosis. An important role in the immune-pathogenesis of AITDs is due to chemokines and cytokines.
