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1. www.cell.com › stem-cell-reports › fulltextSleep deprivation induces corneal epithelial progenitor cell over...

   www.cell.com › stem-cell-reports › fulltext

   28 apr 2022 · The effect of sleep deprivation on adult stem cells is an interesting topic. In this study, we proved that sleep deprivation disrupts redox homeostasis in the tear film and induces corneal epithelial progenitor cell (CEPC) over-expansion in an animal model. Topical treatment of antioxidant L-glutathione attenuates CEPC over-proliferation. To the best of our knowledge, our study is the first to ...

2. www.ncbi.nlm.nih.gov › pmc › articlesHuman embryonic stem cell cultivation: historical perspective and...

   www.ncbi.nlm.nih.gov › pmc › articles

   22 feb 2015 · Significant research efforts have thus been put towards human pluripotent stem cell research for advancements in drug development, cell regeneration and delivery of gene therapies. To reach the full therapeutic potential of hESCs, defined and reproducible culture systems must be integrated in order to generate quantities of hESCs and their derivatives that are able to sustain therapeutic ...

3. www.nature.com › articles › s41556/019/0344-zAdvances in stem cell research and therapeutic development

   www.nature.com › articles › s41556/019/0344-z

   17 giu 2019 · Stem Cell Research & Therapy (2023) Despite many reports of putative stem-cell-based treatments in genetic and degenerative disorders or severe injuries, the number of proven stem cell therapies ...

4. pubmed.ncbi.nlm.nih.gov › 33173943The evolution of the cancer stem cell state in glioblastoma ... -...

   pubmed.ncbi.nlm.nih.gov › 33173943

   25 feb 2021 · Cellular heterogeneity is a hallmark of advanced cancers and has been ascribed in part to a population of self-renewing, therapeutically resistant cancer stem cells (CSCs). Glioblastoma (GBM), the most common primary malignant brain tumor, has served as a platform for the study of CSCs. In addition …

5. www.yourharlow.com › 2024/03/06 › the-evolution-of-stem-cellThe Evolution of Stem Cell Therapies in Treating Autism

   www.yourharlow.com › 2024/03/06 › the-evolution-of-stem-cell

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   6 mar 2024 · The Evolution of Stem Cell Therapies in Treating Autism. Promotional features / Wed 6th Mar 2024 at 12:58pm. Stem cell therapy is a relatively new medical intervention made possible only by recent technological innovations in medicine. There has been extensive research in the field, but still much more to do in the area of stem cell therapies ...

6. www.cell.com › stem-cell-reports › fulltextISSCR Guidelines for Stem Cell Research and Clinical Translation:...

   www.cell.com › stem-cell-reports › fulltext

   27 mag 2021 · The updated Guidelines for Stem Cell Research and Clinical Translation describe the ethical principles and best practices for basic, translational, and clinical research involving stem cells and human embryos. The updated Guidelines include new recommendations to address the recent scientific advances involving embryos, stem cell-based embryo models, chimeras, organoids, and genome editing.

7. pubmed.ncbi.nlm.nih.gov › 24607403Evolution of the cancer stem cell model - PubMed

   pubmed.ncbi.nlm.nih.gov › 24607403

   6 mar 2014 · Genetic analyses have shaped much of our understanding of cancer. However, it is becoming increasingly clear that cancer cells display features of normal tissue organization, where cancer stem cells (CSCs) can drive tumor growth. Although often considered as mutually exclusive models to describe tumor heterogeneity, we propose that the genetic ...