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  1. 5 dic 2020 · The ARREST trial is registered with ClinicalTrials.gov, NCT03880565. Findings: Between Aug 8, 2019, and June 14, 2020, 36 patients were assessed for inclusion. After exclusion of six patients, 30 were randomly assigned to standard ACLS treatment (n=15) or to early ECMO-facilitated resuscitation (n=15).

    • Demetris Yannopoulos, Jason Bartos, Ganesh Raveendran, Emily Walser, John Connett, Thomas A Murray, ...
    • 2020
  2. 27 ago 2023 · Having established feasibility through a pilot randomised trial, we did a prospective, randomised controlled study (the ARREST trial) to establish whether the delivery of patients to a cardiac arrest centre reduces deaths.

  3. 13 nov 2020 · To our knowledge, the ARREST trial is the first randomised interventional trial to assess the effect of early ECMO-facilitated resuscitation compared with standard ACLS treatment for survival of patients with out-of-hospital refractory cardiac arrest.

    • Demetris Yannopoulos, Jason Bartos, Ganesh Raveendran, Emily Walser, John Connett, Thomas A Murray, ...
    • 2020
  4. 25 gen 2023 · A previous randomized, controlled trial that compared extracorporeal CPR with conventional CPR in out-of-hospital cardiac arrest owing to ventricular arrhythmias was the ARREST (Advanced ...

  5. The ARREST trial was a phase 2, single-centre, open-label, adaptive, safety and efficacy randomised clinical trial comparing early extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation to standard advanced cardiac life support (ACLS) in adults with out-of-hospital refractory ventricular fibrillation cardiac arrest.

    • Jason A Bartos, Demetris Yannopoulos
    • 2021
  6. 13 nov 2020 · The ARREST trial showed that ECMO was superior to standard ACLS at improving survival to hospital discharge. Description: The goal of the trial was to evaluate extracorporeal membrane oxygenation (ECMO) initiated in the catheterization laboratory compared with standard advanced cardiac life support (ACLS) among patients with out-of ...

  7. 15 giu 2023 · In this randomized trial, we compared targeted mild hypercapnia with targeted normocapnia in adults with coma who had been resuscitated after out-of-hospital cardiac arrest.