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1. yvchen.bol.ucla.eduChen Lab - Home - University of California, Los Angeles

   yvchen.bol.ucla.edu

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   Chen Lab - Home. Welcome to the Chen Lab website! Announcements. April 24, 2024. Congrats to Ximin, Laurence, and Amy for the publication in Nature Metabolism! April 12, 2024. Congrats to Meng-Yin, Chris, Ryan, and team for the publication in Journal of Experimental Medicine! April 1, 2024.

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     Yvonne is also the co-director of the Tumor Immunology and...

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     Our focus is on mammalian systems, particularly in...

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     Advances in promoting chimeric antigen receptor T cell...

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3. www.uclahealth.org › cancer › membersYvonne Y. Chen, PhD - Member Directory - UCLA Health

   www.uclahealth.org › cancer › members

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   Dr. Yvonne Chen's research focuses on applying molecular and synthetic biology techniques to rewire and construct novel biological circuits for applications in health and medicine, particularly in cell-based immunotherapy.

4. stemcell.ucla.edu › news › member-spotlight-yvonne-chenMember Spotlight: Yvonne Chen is engineering ‘stronger and...

   stemcell.ucla.edu › news › member-spotlight-yvonne-chen

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   15 giu 2023 · Meet Yvonne Chen, PhD, who designs novel strategies to make CAR-T cell immunotherapies safer and more effective for cancer treatment.

5. scholar.google.com › citations‪Yvonne Y. Chen‬ - ‪Google Scholar‬

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   2020. Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems. YY Chen, MC Jensen, CD Smolke. Proceedings of the National Academy of Sciences 107 (19), 8531-8536. , 2010. 316. 2010. Navigating CAR-T cells through the solid-tumour microenvironment. AJ Hou, LC Chen, YY Chen.

6. profiles.ucla.edu › yvonneYvonne Chen | UCLA Profiles

   profiles.ucla.edu › yvonne

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   Chen X, Chen LC, Khericha M, Meng X, Salvestrini E, Shafer A, Iyer N, Alag AS, Ding Y, Nicolaou DM, Chen YY. PMID: 36409926; PMCID: PMC9898126. View in: PubMed Mentions: 2 Fields: All Allergy and Immunology Neo Neoplasms. The sound of silence: Transgene silencing in mammalian cell engineering.

7. pubmed.ncbi.nlm.nih.gov › 33972771Navigating CAR-T cells through the solid-tumour microenvironment

   pubmed.ncbi.nlm.nih.gov › 33972771

   The adoptive transfer of T cells that are engineered to express chimeric antigen receptors (CARs) has shown remarkable success in treating B cell malignancies but only limited efficacy against other cancer types, especially solid tumours.

8. stemcell.ucla.edu › member-directory › yvonne-y-chen-phdYvonne Y. Chen, Ph.D. | UCLA BSCRC

   stemcell.ucla.edu › member-directory › yvonne-y-chen-phd

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   Yvonne Chen, Ph.D., applies biomolecular engineering and synthetic biology principles to advance the development of next-generation adoptive CAR-T cell therapies for cancer. She seeks to enhance the safety, efficacy and applicability of these immunotherapy approaches across a wide range of cancer types. Adoptive T-cell immunotherapy is the ...