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11989 Ensembl ENSG00000165349 ENSMUSG00000031297 UniProt Q8WY07 P70423 RefSeq (mRNA) NM_032803 NM_001048164 NM_001301840 NM_007515 RefSeq (protein) NP_001041629 NP_116192 NP_001288769 NP_031541 Location (UCSC) Chr X: 70.93 – 70.93 Mb Chr X: 100.12 – 100.13 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cationic amino acid transporter 3 is a protein that in humans is encoded by ...
- SLC7A3, ATRC3, CAT-3, CAT3, solute carrier family 7 member 3
1 apr 2013 · The SLC7 family is divided into two subgroups, the cationic amino acid transporters (CATs, SLC7A1–4 and SLC7A14) and the light or catalytic subunits (L-type amino acid transporters (LATs), SLC7A5-13 and SLC7A15) of the heteromeric amino acid transporters (HATs). CATs and LATs belong to the large amino acids, polyamines and organocations (APC ...
- Dimitrios Fotiadis, Yoshikatsu Kanai, Manuel Palacín
- 2013
7 feb 2018 · Cationic amino acid transporters (CATs) belong to the physiologically important solute carrier (SLC) 7 family. Here, the authors present the structure of the mammalian CAT transporter homologue ...
17 dic 2022 · Arginine is one of the most versatile amino acids with many metabolic and regulatory roles, serving as a proteogenic amino acid as well as a precursor for critical molecules, such as nitric oxide ...
21 set 2001 · At least five distinct carrier proteins form the family of mammalian cationic amino acid transporters (CATs). We have cloned a cDNA containing the complete coding region of human CAT-3. hCAT-3 is glycosylated and localized to the plasma membrane. Transport studies in Xenopus laevis oocytes revealed that hCAT-3 is selective for cationic l-amino acids and exhibits a maximal transport activity ...
- Nicole Vékony, Sabine Wolf, Jean-Paul Boissel, Karsten Gnauert, Ellen I. Closs
- 2001
18 apr 2019 · L-Amino acid Transporters (LATs) are asymmetric amino acid exchangers. Here the authors determine the crystal structure of a prokaryotic LAT, the alanine-serine-cysteine exchanger (BasC) and ...
12 ago 2023 · Amino acids are essential for the survival of all living organisms and living cells. Amino acid transporters mediate the transport and absorption of amino acids, and the dysfunction of these proteins can induce human diseases. Cationic amino acid transporters (CAT family, SLC7A1-4, and SLC7A14) are considered to be a group of transmembrane transporters, of which SLC7A1-3 are essential for ...
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