Risultati di ricerca
PubChem. 135403648. DrugBank. DB00650. SMILES. C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O. Indicazioni di sicurezza. Modifica dati su Wikidata · Manuale. L' acido folinico, conosciuto anche come leucovorin, è una miscela dei diasteroisomeri del 5-formilderivato dell’ acido tetraidrofolico.
- C₂₀H₂₃N₇O₇
- C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
- 200-361-6
- 58-05-9
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [2] [3] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning.
- C₂₀H₂₃N₇O₇
- Many
- AU: A
- Intravenous, IM, by mouth
L' acido folico (o acido pteroil-monoglutammico ), noto anche come vitamina M, vitamina B9, o folacina, prende il nome dal latino folium ( foglia ), [2] è stato scoperto nel 1939, dopo una serie di studi relativi alla terapia di una forma di anemia nei polli provocata artificialmente.
- polvere giallo arancione
- 441,403
- C₁₉H₁₉N₇O₆
- 200-419-0
Folate (vitamin B 9) refers to the many forms of folic acid and its related compounds, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid, folacin, and pteroylglutamic acid.
- C₁₉H₁₉N₇O₆
- Folicet, Folvite
- AU: A
- Liver
2 dic 2022 · Folinic acid is a medication used in the treatment of various cancers in combination with 5-FU. It is also commonly used as an antidote to folic acid antagonists such as methotrexate. Folinic acid (leucovorin) is an antidote, chemotherapy modulating agent, and rescue agent for the chemotherapy class of medications.
- Yana D. Gristan, Leila Moosavi
- 2022/12/02
Cerebral folate deficiency is a condition in which concentrations of 5-methyltetrahydrofolate are low in the brain as measured in the cerebral spinal fluid despite being normal in the blood. [3] . Symptoms typically appear at about 5 to 24 months of age.
18 giu 2021 · Folinic acid (leucovorin) is a synthetic vitamer of folic acid having the structure of formyl-THF that could be converted to 5,10-methylene-THF and to 5-methyl-THF without dihydrofolate reductase and has also maximal RFC affinity.
