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  1. Harvard Medical School| HMS · Department of Cell Biology. Contact. Connect with experts in your field. Join ResearchGate to contact this researcher and connect with your scientific community ...

  2. 18 set 2020 · Abstract. Inflammasomes are supramolecular complexes that play key roles in immune surveillance. This is accomplished by the activation of inflammatory caspases, which leads to the proteolytic maturation of interleukin 1β (IL-1β) and pyroptosis.

    • Venkat Giri Magupalli, Venkat Giri Magupalli, Roberto Negro, Roberto Negro, Yuzi Tian, Yuzi Tian, Ar...
    • 2020
  3. 5 feb 2019 · NLRP6 is a sensor protein in the nucleotide-binding domain (NBD) and leucine-rich repeat (LRR)-containing (NLR) inflammasome family that has been shown to play multiple roles in regulating inflammation and host defenses.

    • Chen Shen, Chen Shen, Alvin Lu, Alvin Lu, Wen Jun Xie, Jianbin Ruan, Jianbin Ruan, Roberto Negro, Ro...
    • 2019
  4. Roberto NEGRO | Cited by 7,319 | | Read 122 publications | Contact Roberto NEGRO

  5. wulab.tch.harvard.edu › past-membersPast Members - Wu Lab

    Ph.D., Harvard Chemical Biology Graduate School of Arts and Sciences. Post-Doc Fellow, Harvard Medical School

    • harvard roberto negro1
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  6. Recent studies suggest that TRPM2 is a calcium-permeable cation channel mediating ROS-dependent NLRP3 activation. Here, we review the role of TRPM2 in NLRP3 inflammasome activation and provide an update on new functional and structural discoveries.

  7. Molecular mechanism for NLRP6 inflammasome assembly and activation. Chen Shena,b, Alvin Lua,b,1, Wen Jun Xiec, Jianbin Ruana,b, Roberto Negroa,b, Edward H. Egelmand, Tian-Min Fua,b,2, and Hao Wua,b,2. aDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115; bProgram in Cellular and Molecular ...

  1. Ricerche correlate a "harvard roberto negro"

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