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General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the ...
General paresis (or paralysis) of the insane (GPI) was crippling and terminal. It ended in loss of control over mind and body, often accompanied by grandiose delusions of wealth and power and, finally, paralytic death.
- Kelley Swain
- 2018
James Vance May. James Vance May (1873–1947) was an American psychiatrist [1] and an early proponent for statistical studies and classification of mental diseases. He was among the first to recognize mental disease as a public health problem, a view that did not gain recognition and acceptance for many years. May was born in Lawrence, Kansas.
3 ott 2012 · Learn about the history of general paralysis of the insane (GPI), a fatal disease that affected men in the 19th century. Find out how GPI was linked to syphilis, alcohol, and degeneration, and how it was diagnosed and treated in asylums.
General paresis of insane: A rarity or reality? Suravi Patra and Ajaya Mishra 1. Author information Copyright and License information PMC Disclaimer. Go to: Abstract. There is a widely held clinical opinion that syphilis has disappeared. Contrary to this, there are sporadic cases being reported across the country.
- Suravi Patra, Ajaya Mishra
- 2010
13 gen 2021 · Purpose. We aim to study the clinical manifestations, fluid changes and neuroimaging alterations in patients with general paresis of the insane (GPI). Methods. A total of 119 patients suffering from GPI recruited in Beijing Ditan Hospital, Capital Medical University from 2010 to 2020 were retrospectively analyzed. Results.
General paresis of insane is a progressive disease of the brain leading to mental and physical worsening. It is important to consider tertiary syphilis in the differential diagnosis of dementia.
