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Clinical trials in adolescents included 1 monotherapy trial (AD‑1526) and 1 open-label extension trial (AD‑1434). In AD‑1526, patients were initiated with 2 DUPIXENT (200 mg or 300 mg) doses or placebo (subcutaneous injection) at Week 0 followed by 1 DUPIXENT (200 mg or 300 mg) dose or placebo every 2 weeks, based on the adolescent’s ...
June 25 – The first hurricane ever observed by Europeans strikes the Spanish settlement of La Isabela, on Hispaniola. October 22 – Ludovico Sforza becomes Duke of Milan, and invites Charles VIII of France to invade Italy in support of his claim, beginning the Italian War of 1494–98.
14 aprile - Liduina di Schiedam , mistica olandese (n. 1380) 18 aprile - Cleofe Malatesta , nobile 19 aprile - Piccarda Bueri , italiana (n. 1368) 4 maggio - Pietro Emiliani , politico e vescovo cattolico italiano (n. 1362) 1º giugno - Giacomo II di Urgell , nobile (n. 1380) 14 agosto - Giovanni I del Portogallo , re portoghese (n. 1357) 31 agosto - Pietro I di Lussemburgo-Saint Pol , nobile ...
AD 14 ( XIV) was a common year starting on Monday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Pompeius and Appuleius (or, less frequently, year 767 Ab urbe condita ). The denomination AD 14 for this year has been used since the early medieval period, when the Anno ...
Questa categoria raggruppa voci su eventi avvenuti nell'anno 1434.. Sottocategorie. Questa categoria contiene le 3 sottocategorie indicate di seguito, su un totale di 3.
23 nov 2015 · To assess the long-term efficacy of dupilumab in pediatric participants with AD; To assess the trough concentrations of functional dupilumab in serum and the immunogenicity in pediatric participants with AD after re-treatment with dupilumab; Optional Pre-filled Pen (PFP) Sub-Study in pediatric patients ≥2 to <12 years of age with AD
National Museum of San Marco, Florence. The Deposition from the Cross is a painting of the Deposition of Christ by the Italian Renaissance master Fra Angelico, executed between 1432 and 1434. It is now housed in the National Museum of San Marco, Florence . Giorgio Vasari described it as appearing to have been "painted by a saint or an angel".
