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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made. He was the only son of Prince Augustus Frederick, Duke of Sussex and his wife Lady Augusta Murray.

    • Augustus Frederick Hanover, 13 January 1794, London, Great Britain
    • 28 December 1848 (aged 54), Ramsgate, Kent
  2. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis. For 24 years D’Esté kept a diary, currently held in the Royal College of Physicians’ archives, which documents what he called ...

  3. È singolare che la più antica descrizione sui sintomi e sul decorso clinico della sclerosi multipla, detta anche sclerosi a placche, si debba a Sir Augustus D'Este, nipote del Re Giorgio III d'Inghilterra che tra il 1822 e il 1848 ha scritto in un diario e in un almanacco una cronaca personale della malattia che lo ha colpito.

  4. 17 ott 2009 · Abstract. The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  5. It is a singular fact that the earliest account of the symptoms and clinical history of multiple sclerosis was written by Sir Augustus d'Este, a grandson of King George III of England, who kept a personal diary and record of his disease between 1822 and 1848.

  6. Spencer Compton. Prince Augustus Frederick, Duke of Sussex (27 January 1773 – 21 April 1843), was the sixth son and ninth child of King George III and his queen consort, Charlotte of Mecklenburg-Strelitz. He was the only surviving son of George III who did not pursue an army or navy career.

  7. Abstract. The personal diary of Sir Augustus d’Este ́, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.