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Robert G. Roeder (born June 3, 1942, in Boonville, Indiana, United States) is an American biochemist. He is known as a pioneer scientist in eukaryotic transcription.
- American
A central question in biology is how the transcription of the human genome’s approximately 20,000 genes is regulated in a gene- and cell type-specific manner. Roeder studies the transcription factors, including epigenetic factors, and underlying mechanisms involved in this regulation.
Robert G. Roeder. Arnold and Mabel Beckman Professor. The processes of animal cell growth, differentiation and infection by viruses result from the differential expression of specific genes, controlled primarily at the level of transcription.
Robert G. Roeder has identified in animal cells a series of factors involved in the initiation of transcription from DNA to RNA and has revealed their functions. He elucidated the principle of gene expression mechanisms in eukaryotes and laid the foundation for current life sciences.
Robert G. Roeder has revealed the principle of the regulatory mechanism of transcription in eukaryotes through his over 50 years of transcriptional research, by identifying functions of a series of factors such as three distinct RNA polymerases, basic transcription factors, one of the first gene-specific factors, and regulators in transcription ...
Cited by. Year. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. JD Dignam, RM Lebovitz, RG Roeder. Nucleic acids research 11 (5), 1475-1489. , 1983. 12811. 1983. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain.
Biochemist and molecular biologist. Robert G Roeder has revealed the principle of the regulatory mechanism of transcription in eukaryotes through his over 50 years of transcriptional research, by identifying functions of a series of factors such as three distinct RNA polymerases, basic transcription factors, one of the first gene-specific ...
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