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  1. 30 apr 2024 · Shinya Yamanaka (born September 4, 1962, Ōsaka, Japan) is a Japanese physician and researcher who developed a revolutionary method for generating stem cells from existing cells of the body. This method involved inserting specific genes into the nuclei of adult cells (e.g., connective-tissue cells), a process that resulted in the ...

    • Kara Rogers
  2. 17 apr 2024 · The first iPSC-related patent application (WO2007069666A1) was filed by Kyoto University in 2006; in it, Shinya Yamanaka used Oct3/4, Sox2, c-Myc, and Klf4 as reprogramming factors to induce...

  3. www.mdpi.com › journal › cancersSpecia - MDPI

    23 apr 2024 · made a long time ago by Dr. Shinya Yamanaka who discovered the essential factors needed for pluripotency induction in differentiated cells. All types of cancer contain cancer stem cells representing a small fraction of the bulk tumor, usually around 0.1 – 1% of the total cell number. These cancer stem cells have been shown to be dependent

  4. 26 apr 2024 · Eventually, Takahashi and Yamanaka identified a combination of 4 reprogramming factors—Oct4, Sox2, Klf4, and Myc—that was sufficient to reprogram mouse fibroblasts into embryonic stem cell ...

  5. 4 giorni fa · Subsequently, in 2006, Shinya Yamanakas discovery of induced pluripotent stem cells (iPSCs) revolutionized the field by providing a method to reprogram adult cells into a pluripotent state, offering an ethically acceptable alternative to ESCs [26].

  6. 17 apr 2024 · By Shinya Yamanaka. April 17, 2024 6:59 AM EDT. F or years, Katsuhiko Hayashi, a professor at Osaka University in Japan, has been at the forefront of developmental and reproductive biology,...

  7. 1 giorno fa · Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging. Learn about our FREE Post-Publication Promotion Services