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Laboratory Manager/Administrator: Allison Roach. Stuart Schreiber's lab studies the science of therapeutics. Researchers in his group rely on human biology to identify therapeutic targets that have been validated prior to testing in humans, and chemistry and chemical biology to discover small molecules that modulate the targets in ways required ...
Stuart Schreiber is an American chemist who is the Morris Loeb Research Professor at Harvard University, a co-Founder of the Broad Institute, Howard Hughes Medical Institute Investigator, Emeritus, and a member of the National Academy of Sciences and National Academy of Medicine.
- Organic Synthesis, Chemical Biology, Human Biology, Therapeutics Discovery
Schreiber’s research integrates chemical biology and human biology to advance both our understanding of chemistry and biology, and the discovery of novel therapeutics. He is known for his use of small molecules to explore biology and medicine, and for his role in the development of the field of chemical biology.
1 mar 2024 · Nature Reviews Drug Discovery - Stuart Schreiber discusses his plans to tackle inefficiencies in the translation of biomedical research, through the newly launched for-profit institute Arena...
- Asher Mullard
Stuart Schreiber and his trainees explore the science of small-molecule therapeutics. Group members are synthesizing performance-diverse collections of compounds having unique stereochemical and skeletal features that enable modulation of macromolecules in ways suggested by ‘experiments of nature’ – studies of human biology and patients ...
6 mar 2024 · Harvard chemical biologist Stuart Schreiber first coined the term ’molecular glue’ 2 after his lab showed, using affinity chromatography, that the immunosuppressants cyclosporine and FK506 ...
Stuart L. Schreiber1,2,*. 2021 marks the 30th anniversary of the revelation that cyclosporin A and FK506 act in a way previously not seen—as ‘‘molecular glues’’ that induce neo-protein–protein associations. As a torrent of new molecular-glue probes and medicines are fueling interest in this field, I explore the arc of this story.
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