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Victor R. Ambros (born 1953, Hanover, New Hampshire) is an American developmental biologist who discovered the first known microRNA (miRNA). He is a professor at the University of Massachusetts Medical School in Worcester, Massachusetts .
- Massachusetts Institute of Technology (B.S., 1975) (Ph.D., 1979)
- Biology
- December 1, 1953 (age 69), Hanover, New Hampshire
- discovery of the first known microRNA
In 1993, members of the Ambros lab identified the first microRNA, the product of lin-4, a heterochronic gene of C. elegans. Since then, the role of microRNAs in development has been a major focus of his research. Silverman Professor of Natural Sciences, Professor, Program in Molecular Medicine. Ambros Lab Web Page.
- UMass Chan Medical School 373 Plantation Street Two Biotech Suite 306 Worcester MA 01605
- Professor
- (508) 856-6380
Victor Ambros, PhD Research Focus - Genetic Control of Developmental Timing in C. elegans. Molecular basis of regulated cell fate transitions; Regulation of stem cell proliferation and self-renewal; Coordination of growth and cell fate across the animal; Regulation of mRNA translation by microRNAs and RNA binding proteins; Representative ...
MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. V Ambros. Cell 113 (6), 673-676. , 2003. 1575. 2003. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. EG Moss, RC Lee, V Ambros. Cell 88 (5), 637-646.
13 mag 2012 · Victor Ambros is a professor of molecular medicine at the University of Massachusetts Medical School, and he discovered the first microRNA (miRNA) in 1993. Ambros researched the genetic control of developmental timing in the nematode worm Caenorhabditis elegans , and he helped describe gene function and regulation during the worm’s ...
Victor Ambros was born in Hanover, NH in 1953. He attended the Massachusetts Institute of Technology [MIT] for both his S.B. and his Ph.D. in biology—completing the latter in 1979 with studies of the polio virus genome under his research advisor, Nobel laureate David Baltimore.
6 ott 2022 · Since that early work, says Victor Ambros, who is now at University of Massachusetts Medical School and was lead author of one of the papers, it’s become clear “the short one is the repressor...
