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18 ore fa · TRF2 helps to protect the telomere 3ʹ overhang from being recognized as a DNA double-stranded break by forming a structural cap at the ends of chromosomes to avoid DNA damage responses . TRF2 also blocks the activation sites of PARP1 and ATM kinases, both of which are responsible for triggering DNA damage responses [ 17 , 67 , 68 , 69 ].
18 ore fa · Notable among these PRRs are Toll-like receptors (TLRs) such as TLR3 and TLR7/TLR8, double-stranded RNA-activated protein kinase and members of the retinoic acid-inducible gene I (RIG-I)-like ...
18 ore fa · Additionally, LEA proteins play important roles in maintaining the stability of the cellular matrix in a glassy state, ionic binding, molecular protection, and preservation of enzyme activity and double-stranded DNA binding [17,18,19]. These characteristics make LEA proteins play important role in protecting plants from abiotic stress conditions.
18 ore fa · Lupus-prone MRL/lpr mice were used for the experiments: disease-free (4 weeks of age) and sick (20 weeks of age, virgin and postpartum). The immune response was monitored by flow cytometry, ELISpot, ELISA, and histology. Oocytes were analyzed by fluorescence microscopy based on chromatin, tubulin, and actin structures.
18 ore fa · Double-stranded cDNA Synthesis Kit Celemics offers easy-to-use kit with all components needed from RNA fragmentation to double-stranded cDNA synthesis suitable for NGS. View Detail >
18 ore fa · The principles and advantages of constructing self-complementary double-stranded AAV (scAAV) Recombinant adeno-associated virus (rAAV) serves as a gene delivery vector in vivo, where the necessary condition for transcription to proceed is the conversion of the genome sequence from single-stranded AAV (ssAAV) to double-stranded AAV.
18 ore fa · Each vial contains 150 ng synthetic double-stranded DNA. Resuspend in 30 μL autoclaved deionized water or TE buffer. To prevent contaminating samples and reagents, it is strongly recommended that the Positive Control is resuspended in a separate location from where PCR reactions are set up. Use a different pipette than one used for PCR set up.
