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1 giorno fa · Background TFEB/6p21/VEGFA-amplified renal cell carcinoma (RCC) is rare and difficult to diagnose, with diverse histological patterns and immunohistochemical and poorly defined molecular genetic characteristics. Case presentation We report a case of a 63-year-old male admitted in 2017 with complex histomorphology, three morphological features of clear cell, eosinophilic and papillary RCC and ...
19 ore fa · A significant difficulty is distinguishing clear cell renal cell carcinoma (ccRCC), which is typically associated with a poor outcome, from other non-ccRCC types with a better prognosis. Although the difference in enhancement patterns between ccRCC and papillary RCC is remarkable and helps in effective differentiation, distinguishing ccRCC from chromophobe RCC is more complex [ 3 ].
4 giorni fa · Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype arising from renal cell carcinomas. This tumor is characterized by a predominant angiogenic and immunogenic microenvironment that interplay with stromal, immune cells, and tumoral cells.
1 giorno fa · Kidney Clear Cell Carcinoma (KIRC), the predominant form of kidney cancer, exhibits a diverse therapeutic response to Immune Checkpoint Inhibitors (ICIs), highlighting the need for predictive models of ICI efficacy. Our study has constructed a prognostic model based on 13 types of Programmed Cell Death (PCD), which are intertwined with tumor progression and the immune microenvironment ...
2 giorni fa · Hyaluronan (HA) accumulation in clear cell renal cell carcinoma (ccRCC) is associated with poor prognosis; however, its biology and role in tumorigenesis are unknown. RNA sequencing of 48 HA ...
1 giorno fa · Background: Our purpose is to evaluate the long-term oncologic efficacy and survival rates of MRI-guided cryoablation for patients with biopsy-proven cT1a renal cell carcinoma (RCC). Materials and Methods: We retrospectively reviewed our renal ablation database between January 2007 and June 2021 and only included patients with solitary-biopsy-proven cT1a RCC (≤4 cm) who underwent MRI-guided ...
1 giorno fa · Findings from a retrospective cohort study showed that patients with metastatic non–clear cell renal cell carcinoma (ccRCC) who underwent metastasectomy and radical nephrectomy experienced ...
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