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A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes unconsciousness.
Local anaesthesia involves numbing an area of the body using a type of medicine called a local anaesthetic. These medicines can be used to treat painful conditions, prevent pain during a procedure or operation, or relieve pain after surgery. Unlike general anaesthetics, local anaesthetics don't cause you to lose consciousness.
Gli anestetici locali sono farmaci che agiscono inibendo la conduzione nervosa, bloccando i canali del sodio presenti su tutte le membrane delle cellule eccitabili, provocando così la perdita di sensibilità in una regione limitata del corpo, senza portare necessariamente alla perdita di coscienza.
3 dic 2019 · Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated Na+ channels. In doing so, they inhibit action potentials in nociceptive fibres and so block the transmission of pain impulses.
28 ago 2023 · Local anesthetics block voltage-gated sodium channels, which prevents sodium influx into the cell and blocks impulse transmission. Local anesthetics are also class I antiarrhythmic drugs due to the blockade of cardiac sodium channels, with lidocaine being the class IB prototype.
- Emily H. Garmon, Martin R. Huecker
- 2023/04/09
- 2019
26 gen 2018 · Local anesthesia refers to using a drug called an anesthetic to temporarily numb a small area of your body. Your doctor might use a local anesthetic before doing a minor procedure, such...
16 nov 2023 · Local anesthetics (LAs) are used to block transmission of impulses in nerve fibers, to reduce or eliminate sensation. LAs may be used for neuraxial analgesia and anesthesia, peripheral nerve blocks, subcutaneous and tissue infiltration, and topical anesthesia.
